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Valuation: Septerna, Inc.

Market Cap 1.62B 1.4B 1.29B 1.21B 2.27B 154B 2.3B 15.23B 5.93B 75.19B 6.09B 5.97B 261B P/E Ratio 2026 *
-21x
P/E Ratio 2027 * -15.1x
Enterprise Value 1.28B 1.1B 1.01B 950M 1.78B 121B 1.8B 11.96B 4.66B 59.04B 4.79B 4.68B 205B EV / Sales 2026 *
16.6x
EV / Sales 2027 * 16.9x
Free-Float
97.17%
Yield 2026 *
-
Yield 2027 * -
1 day-1.07%
1 week+15.32%
Current month+18.41%
1 month+35.97%
3 months+42.24%
6 months+36.33%
Current year+28.26%
1 week 30.41
Extreme 30.41
37.01
1 month 25.79
Extreme 25.79
37.01
Current year 22.78
Extreme 22.78
37.01
1 year 9.85
Extreme 9.8515
37.01
3 years 4.17
Extreme 4.17
37.01
5 years 4.17
Extreme 4.17
37.01
10 years 4.17
Extreme 4.17
37.01
Manager TitleAgeSince
Chief Executive Officer 60 01/11/2021
Director of Finance/CFO 55 06/01/2025
President 58 01/08/2025
Director TitleAgeSince
Director/Board Member 60 01/11/2021
Chairman 50 01/11/2021
Director/Board Member 41 01/11/2021
Date Insider Type Main position Quantity % Market Cap.
06-01Fiscal year

Head of Human Resources

17,805 0.0395%
05-26Fiscal year

Head of Human Resources

35,394 0.0788%
04-15Fiscal year

Chairperson

12,000 0.0267%
Change 5-day change 1-year change 3-year change Capi.($)
-1.07%+15.32%+239.28% - 1.62B
-0.12%-0.18%-12.80%-12.90% 43.58B
-2.41%+4.63%+293.45%+535.56% 34.03B
+0.23%-3.89%+12.41%-17.13% 29.77B
-1.06%-0.50%+0.91%+33.27% 29.82B
-0.29%+9.47%+13.95%+21.93% 25.42B
+4.75%+9.29% - - 13.87B
-0.93%-0.70%+54.00%+108.96% 13.35B
-1.04%-3.48%+2.42%+1.98% 12.85B
-0.95%-1.64%+108.17%+78.84% 12.22B
Average -0.32%+3.67%+79.09%+93.81% 21.65B
Weighted average by Cap. -0.47%+2.14%+62.37%+105.17%

Financials

2026 *2027 *
Net sales 76.94M 66.31M 61.06M 57.33M 108M 7.27B 109M 722M 281M 3.56B 289M 283M 12.35B 65.86M 56.76M 52.27M 49.07M 92.14M 6.23B 93.11M 618M 241M 3.05B 247M 242M 10.57B
Net income -76.38M -65.83M -60.62M -56.91M -107M -7.22B -108M -716M -279M -3.54B -287M -281M -12.26B -121M -104M -96.08M -90.21M -169M -11.45B -171M -1.14B -442M -5.61B -454M -445M -19.43B
Net Debt -349M -301M -277M -260M -488M -32.99B -493M -3.27B -1.27B -16.15B -1.31B -1.28B -55.98B -508M -438M -403M -379M -711M -48.07B -719M -4.77B -1.86B -23.54B -1.91B -1.87B -81.58B
Logo Septerna, Inc.
Septerna, Inc. is a clinical-stage biotechnology company. The Company is developing G protein-coupled receptor (GPCR) oral small-molecule drug discovery powered by its proprietary Native Complex Platform. Its pipeline of product candidates is focused on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. Its industrial-scale Native Complex Platform is designed to target certain GPCRs for the first time, uncover novel binding pockets for validated receptors, and pursue a wide spectrum of pharmacologies, including agonists, antagonists, and allosteric modulators, to achieve desired therapeutic effects. It is advancing a deep portfolio of oral small molecule GPCR-targeted programs with novel mechanistic approaches to treat diseases across multiple therapeutic areas for patients with unmet needs. It is focused on therapeutic areas, such as neurology, women’s health, cardiovascular, and respiratory disease.
Employees
130
Date Price Change Volume
16/06/26 35.71 $ -0.89% 112,965
15/06/26 36.03 $ +0.22% 287,821
12/06/26 35.95 $ +5.64% 475,864
11/06/26 34.03 $ +11.68% 513,326
10/06/26 30.47 $ -1.74% 171,877
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
10
Last Close Price
36.03USD
Average target price
45.78USD
Spread / Average Target
+27.05%

Quarterly revenue - Rate of surprise

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