Valuation: Karyopharm Therapeutics Inc.

Market Cap 216M 188M 174M 160M 302M 20.76B 309M 2.08B 817M 10.17B 809M 792M 34.99B P/E 2026 *
-2.28x
P/E 2027 * -3.07x
Enterprise Value 469M 409M 378M 348M 656M 45.12B 671M 4.52B 1.78B 22.1B 1.76B 1.72B 76.07B EV / Sales 2026 *
3.41x
EV / Sales 2027 * 1.39x
Free-Float
95.32%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Karyopharm Therapeutics Inc.

1 day-13.93%
1 week-17.11%
Current month-14.74%
1 month-7.44%
3 months-6.82%
6 months+40.00%
Current year+13.18%
1 week 8.29
Extreme 8.29
10.17
1 month 8.29
Extreme 8.29
10.86
Current year 5
Extreme 5
10.99
1 year 3.65
Extreme 3.6503
10.99
3 years 3.51
Extreme 3.51
29.25
5 years 3.51
Extreme 3.51
220.95
10 years 3.51
Extreme 3.51
444.15
Manager TitleAgeSince
Chief Executive Officer 58 03/05/2021
Director of Finance/CFO 55 03/01/2025
Chief Tech/Sci/R&D Officer - 01/04/2023
Director TitleAgeSince
Director/Board Member 62 01/01/2013
Director/Board Member 61 01/04/2013
Director/Board Member 78 03/10/2013
Date Insider Type Main position Quantity % Market Cap.
21/05/26 Free

Director

15,508 0.0688%
21/05/26 Free

Director

15,508 0.0688%
21/05/26 Free

Director

15,508 0.0688%
Change 5-day change 1-year change 3-year change Capi.($)
-13.93%-17.11%+107.21%-65.51% 216M
-0.47%+1.27%+23.10%-7.12% 68.85B
-0.33%+1.23%+37.62%+190.57% 52.13B
+0.94%+39.60%+39.60%+39.60% 43.46B
-0.58%+1.05%-51.98%-53.78% 41.24B
-1.46%-2.88%+65.48%-26.10% 30.41B
-0.11%-8.09%+98.87%-50.64% 24.53B
-0.64%+2.57%+73.89%+83.05% 23.42B
+3.99%+3.82%+4.34%+196.00% 19.75B
+0.11%+0.22%+71.82%+126.13% 16.57B
Average -1.27%-1.32%+47.00%+43.22% 32.06B
Weighted average by Cap. -0.07%+0.07%+32.99%+46.18%

Financials

2026 *2027 *
Net sales 137M 120M 111M 102M 192M 13.21B 196M 1.32B 520M 6.47B 515M 504M 22.28B 155M 136M 125M 115M 218M 14.96B 222M 1.5B 589M 7.32B 583M 570M 25.21B
Net income -121M -106M -97.59M -89.96M -170M -11.65B -173M -1.17B -459M -5.71B -454M -445M -19.65B -135M -118M -108M -100M -188M -12.96B -193M -1.3B -510M -6.35B -505M -494M -21.84B
Net Debt 253M 221M 204M 188M 354M 24.36B 362M 2.44B 959M 11.93B 950M 929M 41.08B -
Logo Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer. It is developing and commercializing novel, small molecule XPO1 inhibitor compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. XPOVIO is also marketed for treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including myelofibrosis, endometrial cancer and multiple myeloma. The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.
Employees
228
Date Price Change Volume
20/07/26 $8.325 -12.46% 126,814
17/07/26 $9.510 +1.39% 205,243
16/07/26 $9.380 -1.57% 236,381
15/07/26 $9.530 -4.80% 316,488
14/07/26 $10.01 -0.40% 481,544
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
7
Last Close Price
9.510USD
Average target price
13.50USD
Spread / Average Target
+41.96%

Quarterly revenue - Rate of surprise

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