Valuation: Karyopharm Therapeutics Inc.

Market Cap 42.19M 36.15M 33.82M 30.92M 58.35M 4.04B 58.97M 400M 156M 2.03B 158M 155M 6.71B P/E 2026 *
-0.4x
P/E 2027 * -0.78x
Enterprise Value 42.19M 36.15M 33.82M 30.92M 58.35M 4.04B 58.97M 400M 156M 2.03B 158M 155M 6.71B EV / Sales 2026 *
0.31x
EV / Sales 2027 * 0.24x
Free-Float
95.33%
Yield 2026 *
-
Yield 2027 * -
1 day-5.10%
1 week+2.76%
Current month-3.12%
1 month-74.90%
3 months-77.21%
6 months-81.53%
Current year-74.73%
1 week 1.82
Extreme 1.82
2.02
1 month 1.79
Extreme 1.79
7.84
Current year 1.79
Extreme 1.79
10.99
1 year 1.79
Extreme 1.79
10.99
3 years 1.79
Extreme 1.79
29.25
5 years 1.79
Extreme 1.79
220.95
10 years 1.79
Extreme 1.79
444.15
Manager TitleAgeSince
Chief Executive Officer 58 03/05/2021
Director of Finance/CFO 55 03/01/2025
Chief Tech/Sci/R&D Officer - 01/04/2023
Director TitleAgeSince
Director/Board Member 62 01/01/2013
Director/Board Member 61 01/04/2013
Director/Board Member 78 03/10/2013
Date Insider Type Main position Quantity % Market Cap.
28/07/26 Sell

Executive/Senior Manager

-189 0.0008%
14/05/26 Sell

Controller/Auditor

-53 0.0002%
17/02/26 Sell

Executive/Senior Manager

378 0.0021%
Change 5-day change 1-year change 3-year change Capi.($)
-5.10%+2.76%-70.48%-91.08% 42.19M
-0.66%+2.80%+40.55%-0.33% 82.73B
-4.30%+115.47%+412.13%+23.29% 55.45B
+2.85%+10.37%-19.51%-33.87% 57.94B
+1.42%+1.61%-0.67%+34.08% 52.57B
-0.77%+2.14%+11.51%+170.00% 48.94B
+0.62%+4.29%+56.57%-16.88% 32.23B
+0.13%+3.63%+50.49%+99.25% 25.94B
+1.11%+4.09%+0.65%+197.63% 22.1B
-1.74%-1.27%+55.54%+107.91% 16.55B
Average -0.63%+16.26%+53.68%+49.00% 39.45B
Weighted average by Cap. -0.16%+21.99%+75.21%+44.60%

Financials

2026 *2027 *
Net sales 136M 116M 109M 99.41M 188M 12.99B 190M 1.29B 500M 6.52B 509M 498M 21.58B 174M 149M 139M 127M 240M 16.62B 243M 1.65B 640M 8.35B 652M 638M 27.61B
Net income -160M -137M -128M -117M -222M -15.34B -224M -1.52B -591M -7.7B -601M -588M -25.48B -115M -98.47M -92.12M -84.22M -159M -11B -161M -1.09B -424M -5.52B -431M -422M -18.28B
Net Debt - -
Logo Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer. It is developing and commercializing novel, small molecule XPO1 inhibitor compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. XPOVIO is also marketed for treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including myelofibrosis, endometrial cancer and multiple myeloma. The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.
Employees
228
Date Price Change Volume
24/08/26 $1.860 -5.10% 845,772
21/08/26 $1.960 +7.69% 876,794
20/08/26 $1.820 -9.00% 865,646
19/08/26 $2.000 +3.63% 792,127
18/08/26 $1.930 +6.63% 1,145,247
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
5
Last Close Price
1.860USD
Average target price
7.250USD
Spread / Average Target
+289.78%

Quarterly revenue - Rate of surprise

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