Valuation: Karyopharm Therapeutics Inc.

Market Cap 43.51M 37.83M 35.21M 32.32M 61.04M 4.15B 61.99M 415M 163M 2.07B 163M 160M 6.93B P/E 2026 *
-0.43x
P/E 2027 * -0.64x
Enterprise Value 43.51M 37.83M 35.21M 32.32M 61.04M 4.15B 61.99M 415M 163M 2.07B 163M 160M 6.93B EV / Sales 2026 *
0.33x
EV / Sales 2027 * 0.26x
Free-Float
95.32%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Karyopharm Therapeutics Inc.

1 day-72.61%
1 week-74.09%
1 month-79.90%
3 months-78.11%
6 months-70.55%
Current year-73.91%
1 week 1.8
Extreme 1.8
7.84
1 month 1.8
Extreme 1.8
10.86
Current year 1.8
Extreme 1.8
10.99
1 year 1.8
Extreme 1.8
10.99
3 years 1.8
Extreme 1.8
29.25
5 years 1.8
Extreme 1.8
220.95
10 years 1.8
Extreme 1.8
444.15
Manager TitleAgeSince
Chief Executive Officer 58 03/05/2021
Director of Finance/CFO 55 03/01/2025
Chief Tech/Sci/R&D Officer - 01/04/2023
Director TitleAgeSince
Director/Board Member 62 01/01/2013
Director/Board Member 61 01/04/2013
Director/Board Member 78 03/10/2013
Date Insider Type Main position Quantity % Market Cap.
28/07/26 Sell

Executive/Senior Manager

-189 0.0008%
14/05/26 Sell

Controller/Auditor

-53 0.0002%
17/02/26 Sell

Executive/Senior Manager

378 0.0021%
Change 5-day change 1-year change 3-year change Capi.($)
-72.61%-74.09%-51.15%-92.89% 43.51M
+3.29%+16.25%+36.46%+3.19% 76.15B
+2.72%-9.39%+20.58%+172.43% 48.89B
-2.75%+48.50%+48.50%+48.50% 47.83B
-3.81%+7.74%-53.40%-54.31% 41.37B
-2.40%+0.38%+53.81%-24.64% 29.99B
-2.82%+1.57%+58.12%+87.66% 24.23B
-5.35%+1.39%+98.59%-51.89% 21.89B
-1.59%-3.61%-6.77%+150.58% 19.25B
-0.42%+2.89%+77.99%+128.67% 17.14B
Average -8.57%-6.07%+28.27%+36.73% 32.68B
Weighted average by Cap. -0.62%+2.97%+31.45%+43.13%

Financials

2026 *2027 *
Net sales 134M 116M 108M 99.35M 188M 12.77B 191M 1.28B 501M 6.36B 502M 491M 21.31B 169M 147M 136M 125M 236M 16.09B 240M 1.61B 631M 8.01B 633M 619M 26.86B
Net income -125M -108M -101M -92.51M -175M -11.89B -177M -1.19B -466M -5.92B -468M -457M -19.84B -121M -105M -97.83M -89.82M -170M -11.54B -172M -1.15B -453M -5.75B -454M -444M -19.27B
Net Debt - -
Logo Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer. It is developing and commercializing novel, small molecule XPO1 inhibitor compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. XPOVIO is also marketed for treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including myelofibrosis, endometrial cancer and multiple myeloma. The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.
Employees
228
Date Price Change Volume
31/07/26 $1.920 -72.61% 22,398,319
30/07/26 $7.010 +2.19% 4,540,851
29/07/26 $6.860 -3.24% 436,891
28/07/26 $7.090 -.--% 531,286
27/07/26 $7.090 -4.32% 527,473
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
OUTPERFORM
Number of Analysts
6
Last Close Price
1.920USD
Average target price
6.400USD
Spread / Average Target
+233.33%

Quarterly revenue - Rate of surprise

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